Commissioned on October 14, 2000, in a ceremony at her home port in Mayport, Florida, the USS Franklin and Eleanor Roosevelt (DDG-80) is an Arleigh Burke -class Aegis guided missile destroyer. The USS Franklin and Eleanor Roosevelt was named after America's 32nd president and his wife in honor of Franklin Roosevelt's achievements as Commander-in-Chief of the Armed Forces and President of the United States, and Eleanor Roosevelt's commitment and contribution to securing worldwide human rights. Franklin and Eleanor Roosevelt's granddaughter, Nancy Roosevelt Ireland, was the ship's sponsor and officially christened her. The USS Roosevelt joined the Fleet alongside another new destroyer, the USS Winston Churchill (DDG-81). "It is no coincidence that these two ships of the same class and sequential numbers will honor the memories of World War II's Allied leaders, who, together, helped save the world from the rule of hate, tyranny and oppression," Secretary of the Navy John H. Dalton announced in 1996. "These two warships - the newest and most capable our nation has ever built - will sail side by side in defense of freedom and democracy around the world."

Construction on the USS Roosevelt began on January 13, 1997 by the Ingalls Shipbuilding division of Litton Industries in Pascagoula, Mississippi. Eleven months later workers laid the ship's keel and launched her into the sea for a test run in January 1999.

The USS Roosevelt is a symbol of the United States Navy's duties in both peace- and war-time; at any time she can execute missions, participate in sea control operations, or simply serve the Fleet in excercises of power projection. At 509.5 feet, she displaces at about 9,204 tons and is the home to a crew of approximately 340. Powered by four gas turbine engines, she can make speeds in excess of 30 knots. New technologies have made the USS Roosevelt very powerful and versatile. She can operate independently or as a support ship for other naval vessels such as an aircraft carrier. She is equipped for air, surface, and subsurface conflict with Standard surface-to-air missiles, Tomahawk surface-to-surface cruise missiles, Vertical Launch ASROC (VLA) missiles, Phalanx close-in weapons system (CIWS), Harpoon anti-ship missiles, one 5"/54 caliber Mk-45 (lightweight gun), and an advanced anti-submarine system.

The USS Roosevelt is stationed in Mayport, Florida.